Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Email this article to a Colleague Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to My Articles & Searches Download to citation manager Citing Articles via HighWire Citing Articles via Google Scholar Articles by Megna, J. L. Articles by Dewan, M. Search for Related Content PubMed Citation Articles by Megna, J. L. Articles by Dewan, M. Chronically Mentally Ill Patients Outpatient Services

A Naturalistic Study of Risperidone Maintenance Treatment of Outpatients With Severe Mental Illness

In a naturalistic study of the effectiveness of atypical antipsychotics for the long-term outpatient treatment of persons with severe and persistent mental illness, 19 patients began taking risperidone and were prospectively evaluated. Nine patients dropped out of risperidone treatment before three months; four of them later responded to clozapine. The ten patients who completed the study on risperidone were less severely ill at baseline. Three completers with unremitting negative symptoms required a combination of risperidone and typical antipsychotics. The results suggest that risperidone is effective for about half of patients with severe and persistent mental illness. Very ill patients who are not responsive to risperidone or combined antipsychotic therapy will likely benefit from clozapine.

This article has been cited by other articles:

				C. U. Correll, S. Leucht, and J. M. Kane Lower Risk for Tardive Dyskinesia Associated With Second-Generation Antipsychotics: A Systematic Review of 1-Year Studies Am J Psychiatry, March 1, 2004; 161(3): 414 - 425. [Abstract] [Full Text] [PDF]

Get information about faster international access.

Privacy Policy

Copyright © 1999 American Psychiatric Association. All rights reserved.

Home | Search | Current Issue | Past Issues | Subscribe | All APPI Journals | Help | Contact Us